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Weight loss injection
Wegovy weight loss injections
Order weekly Wegovy GLP-1 injection pens that reduce appetite and support sustainable weight loss.
- Self-inject once a week
- Lose an average of 20.7% of body weight over 72 weeks*
- Shown to reduce heart risk**
Available doses
R1,690R1,873
Price with Subscribe & Save
*STEP UP, a 72-week study in adults with obesity using semaglutide 7.2 mg. **SELECT study. Individual results may vary. Indicative starting dose for reference; your doctor determines the right dose.
About Wegovy
What is Wegovy and how does it work?
Wegovy is a prescription-only medicine containing semaglutide, a GLP-1 receptor agonist. It mimics a hormone released after eating, which slows stomach emptying and reduces hunger signals in the brain.
How it works
Semaglutide acts on GLP-1 receptors to reduce hunger and 'food noise', making it easier to eat less without constantly relying on willpower.
How effective is it?
In clinical studies, adults lost an average of 20.7% of their body weight over 72 weeks, alongside changes to diet and exercise.
How quickly will you see results?
Most people notice reduced appetite within the first few weeks. Weight change gradually increases as the dose is built up.
In short
Wegovy summary
| Detail | Information |
|---|---|
| Active ingredient | Semaglutide |
| Form | Weekly injection pen |
| Manufacturer | Novo Nordisk |
| Price | R1,690–R4,199 per pen |
| Availability | In stock |
| Strengths | 0.25 mg, 0.5 mg, 1mg, 1.7 mg, 2.4 mg, 7.2 mg |
| Review | Our doctors assess whether the treatment is suitable and monitor your progress. They adjust your dose if needed. |
| Support | Medical team available throughout your journey |
| Monitoring | Regular check-ins with our medical team during treatment |
Real Wegovy results from our patients
People come to us for different reasons, but most are looking for a safe, guided way to manage their weight.
20.7%
body weight lost (in studies)*
9 in 10
reported health improvements
7 in 10
reported greater confidence
*Based on clinical study results and patient-reported outcomes. Individual results may vary.
How to get Wegovy
The first steps toward feeling healthier.
Complete a simple questionnaire
Answer questions about your health, lifestyle and goals.
Your request is reviewed by a doctor
An HPCSA-registered doctor carefully reviews your request to check the treatment is safe and suitable for you.
Receive discreet delivery
Your medication is prepared by our registered pharmacy and discreetly packaged for delivery to your door.
Stay supported
Schedule check-ins with our specialist team to track your progress and support you throughout your journey.
Understanding side effects
Most side effects relate to digestion and occur early in treatment or after a dose increase. For most people they're mild to moderate and ease as the body adjusts.
Digestive issues
Nausea, diarrhoea, vomiting, constipation, indigestion and burping are the most common effects, usually strongest in the first few weeks and after each dose increase.
Other common side effects
Headache, dizziness, tiredness, injection site reactions and temporary hair loss linked to rapid weight loss.
Dehydration
Persistent nausea, vomiting or diarrhoea can lead to dehydration. Drink fluids regularly and tell your doctor if symptoms are severe or ongoing.
Less common but serious
Gallbladder problems, pancreatitis and severe allergic reactions are rare. Seek help immediately for severe abdominal pain with vomiting.
Eligibility
Wegovy supports weight management alongside healthy eating and regular exercise. A thorough review is the best way to find the right treatment for you.
Is Wegovy right for me?
- Adults with a BMI of 30 or higher
- Adults with a BMI of 27 or higher plus a weight-related condition such as high blood pressure, high cholesterol or prediabetes
- Lower BMI thresholds may apply for people of South Asian, Chinese, other Asian, Middle Eastern, Black or African-Caribbean background
- People able to commit to lifestyle changes alongside treatment
Who shouldn't use Wegovy?
- Under 18 or over 85
- Pregnant or breastfeeding
- Allergic to semaglutide or any of the pen's ingredients
- Personal or family history of medullary thyroid carcinoma, or MEN2
- Severe kidney or liver problems, pancreatitis or severe gastrointestinal conditions
- Currently taking other GLP-1 medicines or blood sugar-lowering medicines
Results
What Wegovy weight loss results can look like. Individual results may vary.
What to expect over time
Most people see steady weight loss in the first year, with results maintained as long as they continue treatment alongside changes to diet and exercise.
Clinical study data
- STEP 1: 14.9% average loss at 2.4 mg over 68 weeks
- STEP UP: 20.7% average loss at 7.2 mg over 72 weeks
- SELECT: reduced risk of major cardiovascular events
Head-to-head comparison
In SURMOUNT-5, semaglutide led to an average 13.7% weight loss, compared with 20.2% for tirzepatide over 72 weeks.
Body composition
Most of the weight lost comes from fat mass, but preserving muscle mass through regular exercise and adequate protein is important throughout treatment.
Mounjaro versus Wegovy at a glance
Both are weekly injections prescribed for weight loss. They work in different ways, and the right choice depends on how your body responds, not just the numbers.
| Quick comparison | Mounjaro | Wegovy |
|---|---|---|
| How it works | Dual GIP and GLP-1 receptor agonist | GLP-1 receptor agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Average weight change at 72 weeks* | 20.2% reduction | 13.7% reduction |
| Dosing | Injected once weekly | Injected once weekly |
| Common side effects | Mainly gastrointestinal | Mainly gastrointestinal |
*SURMOUNT-5 directly compared the maximum tolerated doses of tirzepatide and semaglutide, alongside lifestyle support, in adults with obesity without type 2 diabetes. Individual results may vary.
Taking it and dosing
Wegovy dosage
Treatment starts at 0.25 mg per week and is built up every 4 weeks until you reach the dose that works best for you.
| Weeks | Dose | Notes |
|---|---|---|
| Weeks 1–4 | 0.25 mg | Starting dose |
| Weeks 5–8 | 0.5 mg | Building up |
| Weeks 9–12 | 1mg | Building up |
| Weeks 13–16 | 1.7 mg | Building up |
| Week 17 onwards | 2.4 mg | Maintenance dose |
| Higher dose | 7.2 mg | Only if clinically appropriate |
Doses are gradually built up to reduce side effects. Never adjust your dose without discussing it with your doctor.
How to use the Wegovy injection
Use Wegovy once a week, on the same day if possible, at any time of day.
Missed doses
- Less than 5 days late — take the missed dose as soon as you remember
- More than 5 days — skip it and take your next dose on the usual day
- Never take a double dose
Injection sites
- Stomach, at least 5 cm from the belly button
- Thigh
- Upper arm
- Rotate the injection site each week
How to inject
- Wash your hands and check the pen and expiry date
- Attach a new needle and check the medicine is clear and colourless
- Inject and hold for 6 seconds until the dose counter reaches 0
- Dispose of the needle in a sharps container
Support at every step
Your doctor or pharmacist can guide you through using it before you start treatment. Injecting usually gets easier with practice.
Important safety information
Contraindications, interactions and when to seek urgent help.
Don't use Wegovy if you
- Are allergic to semaglutide or any of the pen's ingredients
- Have a personal or family history of medullary thyroid carcinoma
- Have Multiple Endocrine Neoplasia syndrome type 2
- Are pregnant or breastfeeding
Check with your doctor first if you
- Have a history of pancreatitis or gallstones
- Have a severe gastrointestinal condition
- Have kidney problems
- Have diabetic retinopathy
Interactions
- Insulin and sulfonylureas increase the risk of low blood sugar
- Other GLP-1 medicines should not be combined
- Delayed stomach emptying can affect absorption of some oral medicines
- Alcohol can worsen nausea and affect blood sugar
When to seek urgent help
- Severe abdominal pain radiating to the back
- Persistent vomiting
- Severe upper abdominal pain with fever
- Signs of a severe allergic reaction
Storage & travel
Storing your Wegovy pen
Store unopened pens in the fridge at 2–8°C in the original packaging, and don't freeze them. Once in use, a pen can be kept below 30°C for up to 28 days.
How we deliver your Wegovy
Wegovy is shipped in validated temperature-controlled packaging with cool packs that maintain fridge conditions for at least 48 hours.
Can I travel with Wegovy?
Yes. Use an insulated travel bag with cool packs, keep a barrier between the cool pack and the pen, and carry it in your hand luggage.
Prescription letters
You may need a letter for airport security. Contact us and your doctor will send a PDF copy to print.
Stopping, restarting and switching
Talk to your doctor before changing your treatment. A clear plan gives you the best chance of maintaining your results.
Can you stop suddenly?
Yes — semaglutide doesn't cause physical withdrawal. The medicine leaves your body within a few weeks.
What happens after stopping?
Appetite often returns to pre-treatment levels, and some weight regain is common. Our team helps with nutrition and lifestyle planning to maintain results.
Restarting Wegovy
- Within a few weeks — restart at your last tolerated dose
- After a longer break — you may need to restart at 0.25 mg and build up again
Switching to or from Mounjaro
- Leave one week between your last Wegovy dose and your first Mounjaro dose, starting at 2.5mg
- Switching from Mounjaro to Wegovy also requires a one-week gap; your doctor will advise the starting dose.
Wegovy alternatives
Wegovy is one of several prescription weight loss treatments, and it isn't always the right starting point for everyone.
Weight loss injections
- Mounjaro — tirzepatide, weekly, dual GIP and GLP-1 action
- Saxenda — liraglutide, daily, a more gradual approach
- Generic liraglutide — the same active ingredient at a lower price
Weight loss pills
- Wegovy pill — prescription-only oral semaglutide
- Foundayo — once-daily oral treatment
- Orlistat — reduces the amount of fat absorbed from food
Wegovy prices
The price depends on the prescribed strength and generally increases as your dose rises. Each pen lasts four weeks.
| Dose | Stage | Price per pen | Subscribe & Save |
|---|---|---|---|
| 0.25 mg | Starting dose | R1,873.00 | R1,690.00 |
| 0.5 mg | Building up | R2,249.00 | R2,024.00 |
| 1mg | Building up | R2,624.00 | R2,362.00 |
| 1.7 mg | Building up | R3,185.00 | R2,866.00 |
| 2.4 mg | Maintenance | R3,746.00 | R3,371.00 |
| 7.2 mg | Higher dose | R4,199.00 | R3,779.00 |
Prices are per pen. Subscribe & Save is optional. Your doctor confirms the right dose based on your review.
Wegovy build-up schedule
Your body needs time to adjust to each dose. This schedule shows when to order your next pen and what to expect over 20 weeks.
0.25 mg
1–2 kg
0.5 mg
2–3 kg
1mg
3–4 kg
1.7 mg
4–5 kg
2.4 mg
5–6 kg
Expected weight loss figures are estimates based on clinical data. Individual results depend on diet, exercise and adherence.
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Reviewers overwhelmingly report a great experience. Customers praise the efficiency and professionalism of the service, the simple ordering process, fast and reliable delivery, and a support team that is helpful, responsive and genuinely engaged.
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Their service is exceptional, very thorough and efficient.
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Best online pharmacy I've ever used
They're so helpful and efficient and respond quickly. I'll definitely use this service again.
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Very trustworthy company
I was reviewed by a doctor before any decision was made. That gives me confidence it's a trustworthy company. It arrived in an insulated box with a cool pack, and my order went smoothly.
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The experience has changed my life
I've lost a significant amount of weight and I'm no longer hungry, so I don't overeat. The guidance along the way has really kept me on track.
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Fast, efficient and knowledgeable
Miva has guided me through my weight-loss journey. The service is fast, but there's always knowledgeable support in the background.
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Fast and simple
I filled out a thorough questionnaire, uploaded photos and the prescription was sent within the hour. The usage instructions were very detailed.
Our team of specialists
Our clinical team of doctors, pharmacists, dietitians and health coaches supports you at every stage. Join over 1 million patients who trust Miva with their health.
Dr. Lydia Sham Rashid
Head Physician
MD
Dr. Shehna Raghoonanan
Doctor
MB ChB
Abdal Alvi
Chief Clinical Officer
MPharm, IP, MRPharmS
Laura Perez
Head of Clinical Nutrition
BSc (Hons), MSc, MSc
Aamina Rafiq
Responsible Pharmacist
MPharm
Ayisha Mushtaq
Registered Nutritionist
MSc Human Nutrition
Zahra Qureshi
Clinical Pharmacist
MPharm, IP
Richard Wood
Clinical Pharmacist
MPharm, IP
Rebekkah Shaw
Head of Patient Care
BSc (Hons)
Jane Miller
Registered Dietitian
MSc, RD
Frequently asked questions about Wegovy
Weight loss treatments
Medically reviewed by
Aamina Rafiq
Responsible Pharmacist
This page has been reviewed by our clinical team to ensure the information is clear, accurate and up to date. Last updated: 10 February 2026.
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